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Journal of Rehabilitation Research and Development
Vol. 39 No. 5, September/October 2002
Pages 597-608


Investigation of lower-limb tissue perfusion during loading

M.B. Silver-Thorn, PhD

Marquette University, Department of Biomedical Engineering, 1515 West Wisconsin Avenue, Olin Engineering
Center, Room 338A, Milwaukee, WI


Abstract—An extant tissue indentor used for amputee residual limb tissue indentation studies was modified to include laser Doppler flowmetry (LDF) to enable measurement of tissue perfusion during indentation. This device allows quantitative assessment of the mechanical and physiological response of soft tissues to load, as demonstrated by indentation studies of the lower-limb tissues of young healthy subjects. Potential measures of interest include the relative change in tissue perfusion with load and the time delays associated with the perfusion response during tissue loading and unloading. Such measures may prove useful in future studies of residual limb tissues, improving our understanding of tissue viability risk factors for individuals with lower-limb amputation.

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