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Logo for the Journal of Rehab R&D
Volume 41 Number 1, January/February 2004
Pages 1 — 8


Abstract - The relationship between energy expenditure and lean tissue
in monozygotic twins discordant for spinal cord injury

William A. Bauman, MD; Ann M. Spungen, EdD; Jack Wang, MS; Richard N. Pierson, Jr, MD

Department of Veterans Affairs (VA) Rehabilitation Research and Development Center of Excellence, Spinal Cord Damage Research Center, and Medical, Spinal Cord Injury, and Research Services, VA Medical Center, Bronx, NY; Departments of Medicine and Rehabilitation Medicine, Mount Sinai Medical Center, New York, NY; Body
Composition Unit, Columbia University-St. Luke's/Roosevelt Hospital Center, New York, NY
Abstract — Energy expenditure and fat-free mass (FFM), as well as the relationships between these parameters, were investigated in thirteen pairs of monozygotic twins discordant for SCI. Basal energy expenditure (BEE) and resting energy expenditure (REE) were determined by indirect calorimetry. Measurements for FFM and fat mass were obtained by dual-energy x-ray absorptiometry. Total body potassium was determined by a 4-Pi whole-body counting chamber. Values are expressed as mean standard deviation. BEE and REE of the twins with SCI were significantly less than those of the able-bodied co-twins (1387 268 vs. 1660 324 kcal/d, p < 0.005, and 1682 388 vs. 1854 376 kcal/d, p < 0.05, respectively). Regardless of the group, direct and highly significant relationships were evident between BEE or REE and FFM or TBK. In summary, twins with SCI had lower energy expenditure than their able-bodied co-twins. Regardless of paralysis, direct linear relationships existed between energy expenditure and measures of lean mass.
Key words: energy expenditure, fat-free mass, paraplegia, spinal cord injury, total body potassium.

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