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Human genome comparison of paretic and nonparetic vastus lateralis muscle in patients with hemiparetic stroke

Michael J. McKenzie, PhD, CSCS, et al.

Figure.Proposed influences of stroke on skeletal muscle and possible geneclusters induced by these muscle changes.

Stroke is quite debilitating. In addition to the brain, it can have consequences for other organs, such as muscle, which may contribute to further disability. We determined whether gene levels differed between the paretic and nonparetic stroke leg muscles in stroke survivors. These skeletal-muscle gene differences may contribute to weakness, inflammation, and diabetes. This study is the first step toward identification of how these genes are altered after a stroke.

Volume 45 Number 2, 2008
Pages 273 — 282

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