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Volume 45 Number 6, 2008
   Pages 911  — 920

Abstract - Clinical and psychological correlates of two domains of hopelessness in schizophrenia

Paul H. Lysaker, PhD; 1-2* Michelle P. Salyers, PhD; 3-6 Jack Tsai, MS; 1,6 Linda Yorkman Spurrier, MSN, RN; 1 Louanne W. Davis, PsyD 1-2


1 Richard L. Roudebush Department of Veterans Affairs (VA) Medical Center (VAMC), Indianapolis, IN; 2 Indiana University (IU) School of Medicine, Indianapolis, IN; 3 VA Health Services Research and Development Center on Implementing Evidence-Based Practice, Richard L. Roudebush VAMC, Indianapolis, IN; 4 IU Center for Health Services and Outcomes Research, Regenstrief Institute, Inc, Indianapolis, IN; 5 ACT Center of Indiana, Indianapolis, IN; 6 Department of Psychology, IU-Purdue University Indianapolis, Indianapolis, IN

Abstract — Hopelessness is a widely observed barrier to recovery from schizophrenia spectrum disorders. Yet little is known about how clinical, social, and psychological factors independently affect hope. Additionally, the relationships that exist between these factors and different kinds of hope are unclear. To explore both issues, we correlated two aspects of hope, expectations of the future and agency, with stigma, clinical symptoms, anxiety, and coping preferences in 143 persons with a schizophrenia spectrum disorder. Multiple regressions revealed that hope for the future was predicted by lesser alienation, lesser preference for ignoring stressors, and lesser emotional discomfort and negative symptoms, accounting for 43% of the variance. A greater sense of agency was linked to lesser endorsement of mental illness stereotypes, fewer negative symptoms, lesser social phobia, and lesser preference for ignoring stressors, accounting for 44% of the variance. Implications for research and interventions are discussed.

Key words: agency, anxiety, coping, hope, negative symptoms, positive symptoms, recovery, rehabilitation, schizophrenia, social phobia, stigma.

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