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Tissue-engineered intrasynovial tendons: Optimization of acellularization and seeding

Andrew Y. Zhang, MD, et al.

Figure. Acellularized tendon scaffolds reseeded with endotenon cells bysuspension method

When the tendon of the hand is injured or missing from severe trauma, patients cannot use their hands normally and their lives are much harder. To fix the problem, a surgeon usually borrows tendon from other parts of the body to replace the damaged tendon. Our work involves creating new tendon without using tendon from other parts of the body. Our idea is to use the patient's own cells to repopulate a donor tendon that has been treated to have no cells, whereby creating a tendon that is the same as the patient's own.

Volume 46 Number 4, 2009
   Pages 489 — 498

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