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JRRD at a Glance

Pharmacological management of neurobehavioral disorders following traumatic brain injury- A state-of-the-art review

Effie Chew, MD; Ross D. Zafonte, DO

Neurological problems such as problems with arousal, attention, memory, and behavior are common after traumatic brain injury (TBI). Medications are often used to enhance function, memory, and behavior. However, the research supporting this use is scant. This review summarizes the state of our knowledge in prevention of secondary neurological damage, drug treatment of low arousal states, attention and memory problems, aggression, agitation, and mood disorders following TBI. We further recommend the direction of future research, which includes further defining the specific characteristics of patients who will benefit from specific treatments, the time course of treatment, and combination therapy.

Volume 46 Number 6, 2009
   Pages 851 — 878

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