Journal of Rehabilitation Research & Development (JRRD)

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Volume 48 Number 4, 2011
   Pages 355 — 366

Abstract —  Upper-limb robot-assisted therapy in rehabilitation of acute stroke patients: Focused review and results of new randomized controlled trial

Stefano Masiero, MD;1 Mario Armani, MD;2 Giulio Rosati, PhD3*

1Department of Rehabilitation Medicine, University of Padua, Padua, Italy; 2Neuromotor Rehabilitation Unit, Eremo Hospital, Arco (Trento), Italy; 3Department of Innovation in Mechanics and Management, University of Padua, Padua, Italy

Abstract — The successful motor rehabilitation of stroke patients requires early intensive and task-specific therapy. A recent Cochrane Review, although based on a limited number of randomized controlled trials (RCTs), showed that early robotic training of the upper limb (i.e., during acute or subacute phase) can enhance motor learning and improve functional abilities more than chronic-phase training. In this article, a new subacute-phase RCT with the Neuro-Rehabilitation-roBot (NeReBot) is presented. While in our first study we used the NeReBot in addition to conventional therapy, in this new trial we used the same device in substitution of standard proximal upper-limb rehabilitation. With this protocol, robot patients achieved similar reductions in motor impairment and enhancements in paretic upper-limb function to those gained by patients in a control group. By analyzing these results and those of previous studies, we hypothesize a new robotic protocol for acute and subacute stroke patients based on both treatment modalities (in addition and in substitution).

Clinical Trial Registration: ClinicalTrials.gov; NCT01102309, "Robot-assisted rehabilitation of the upper limb in acute and subacute poststroke patients"; http://clinicaltrials.gov/ct2/show/NCT01102309.

Key words: cerebrovascular accident, hemiparesis, recovery of function, rehabilitation, robot, robotics, stroke, subacute therapy, training, upper limb.


View HTML  ¦  View PDF  ¦  Contents Vol. 48, No. 4
This article and any supplementary material should be cited as follows:
Masiero S, Armani M, Rosati G. Upper-limb robot-assisted therapy in rehabilitation of acute stroke patients: Focused review and results of new randomized controlled trial. J Rehabil Res Dev. 2011;48(4):355-66.
DOI:10.1682/JRRD.2010.04.0063
Crossref

Last Reviewed or Updated  Tuesday, May 10, 2011 2:22 PM

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