Fatigue, particularly central fatigue, is one of the most commonly reported symptoms in individuals with multiple sclerosis (MS). However, effective treatments for MS-associated central fatigue have not been established. Surface functional electrical stimulation (FES), which can challenge the peripheral neuromuscular system without overloading the central nervous system, is a relatively safe therapeutic strategy. The current study showed that central fatigue was a primary limitation in MS patients during voluntary exercise, and that 8 weeks of surface FES training led to significantly reduced fatigue, particularly central fatigue, in individuals with MS.
Volume 48 Number 5, 2011
Pages 555 — 564
Last Reviewed or Updated Tuesday, May 24, 2011 1:55 PM