Journal of Rehabilitation Research & Development (JRRD)

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Development of surgical protocol for implantation of tracheal prostheses in sheep

Agn??s Dupret-Bories, MD, et al.

Figure 7. Histological examination of middle of animal 11???s prosthesis. Squa-mous epithelium is present in lumen and pores are infiltrated by fibro-vascular tissues (hematoxylin-eosin-saffron).

Research is necessary to improve the situation of laryngectomees. Therefore, our team is interested in a new project called "artificial larynx." The aim of this project is to develop a totally implantable artificial larynx for laryngectomees. This artificial larynx can be divided in two main parts: (1) a valve system that could make it possible to switch between breathing and speaking, and (2) a prosthesis, made of porous titanium, that will be a connector to fix the artificial larynx to the extremity of upper trachea. The philosophy of the project is to first develop the separate parts. In this article we focus on the integration of the tracheal prosthesis through a long-term study on sheep.

Volume 48 Number 7, 2011
   Pages 851 — 864

View HTML  ¦  View PDF  ¦  Contents Vol. 48, No. 7
This article and any supplementary material should be cited as follows:
Dupret-Bories A, Schultz P, Vrana NE, Lavalle P, Vautier D, Debry C. Development of surgical protocol for implantation of tracheal prostheses in sheep. J Rehabil Res Dev. 2011;48(7):851-64.

Last Reviewed or Updated  Thursday, August 18, 2011 12:35 PM

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