Journal of Rehabilitation Research & Development (JRRD)

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Role of sensory and motor intensity of electrical stimulation on fibroblastic growth factor-2 expression, inflammation, vascularization, and mechanical strength of full-thickness wounds

Mohammad Reza Asadi, MSc, et al.

Electrical stimulation (ES) may be clinically applicable for angiogenesis by stimulating the formation of angiogenic factors. We evaluated the effect of sensory and motor intensities of cathodal current on the release of fibroblastic growth factor-2 (FGF-2) at the wound site and also the biomechanical and histological properties of healed skin. The results showed that skin FGF-2 levels in the sensory group were significantly greater than that in the other groups on the third day. The motor ES induced an increase in the proliferation of collagen and improved the biomechanical properties of the healed skin. It seems that the different intensities of ES should likely be applied for the different stages of healing to obtain optimal effects.
http://dx.doi.org/10.1682/JRRD.2012.04.0074

Volume 50 Number 4, 2013
   Pages 489 — 498


View HTML  ¦  View PDF  ¦  Contents Vol. 50, No. 4
This article and any supplemental material should be cited as follows:
Asadi MR, Torkaman G, Hedayati M, Mofid M. Role of sensory and motor intensity of electrical stimulation on fibroblastic growth factor-2 expression, inflammation, vascularization, and mechanical strength of full-thickness wounds. J Rehabil Res Dev. 2013;50(4):489–98.
http://dx.doi.org/10.1682/JRRD.2012.04.0074
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