Journal of Rehabilitation Research & Development (JRRD)

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Volume 51 Number 3, 2014
   Pages 391 — 400

Abstract — Anomia treatment platform as behavioral engine for use in research on physiological adjuvants to neurorehabilitation

Diane Kendall, PhD;1–2* Anastasia Raymer, PhD;2–3 Miranda Rose, PhD;4–5 JoEllen Gilbert, MS;2,6 Leslie J. Gonzalez Rothi, PhD2,7

1Department of Speech and Hearing Sciences, University of Washington, Seattle, WA; 2Brain Rehabilitation and Research Center, Malcom Randall Department of Veterans Affairs Medical Center, Gainesville, FL; 3Department of Communication Disorders and Special Education, Old Dominion University, Norfolk, VA; 4School of Human Communication Sciences, La Trobe University, Melbourne, Australia; 5Clinical Centre for Research Excellence in Aphasia Rehabilitation, University of Queensland, Queensland, Australia; 6Department of Neurology Research, University of Florida/Shands Neuroscience Center, Jacksonville, FL; 7The Bob Paul Family Professor of Neurology, University of Florida, Gainesville, FL

Abstract — The purpose of this study was to create a "behavioral treatment engine" for future use in research on physiological adjuvants in aphasia rehabilitation. We chose the behavioral target anomia, which is a feature displayed by many persons who have aphasia. Further, we wished to saturate the treatment approach with many strategies and cues that have been empirically reported to have a positive influence on aphasia outcome, with the goal being to optimize the potential for positive response in most participants. A single-subject multiple baseline design with replication across eight participants was employed. Four men and four women, with an average age of 62 yr and an average of 63.13 mo poststroke onset, served as participants. Word-retrieval treatment was administered 3 d/wk, 1 h/d for a total of 20 treatment hours (6–7 wk). Positive acquisition effects were evident in all eight participants (d effect size [ES] = 5.40). Treatment effects were maintained 3 mo after treatment termination for five participants (d ES = 2.94). Within and across semantic category, generalization was minimal (d ES = 0.43 within and 1.09 across). This study demonstrates that this behavioral treatment engine provides a solid platform on which to base future studies whereby various treatment conditions are manipulated and pharmacologic support is added.

Key words: adjuvant, anomia, aphasia, behavioral treatment engine, language, neurorehabilitation, pharmacology, rehabilitation, speech-language pathology, stroke.


View HTML ¦ View PDF ¦ Contents Vol. 51, No.3
This article and any supplementary material should be cited as follows:
Kendall D, Raymer A, Rose M, Gilbert J, Gonzalez Rothi LJ. Anomia treatment platform as behavioral engine for use in research on physiological adjuvants to neurorehabilitation. J Rehabil Res Dev. 2014;51(3):391–400.
http://dx.doi.org/10.1682/JRRD.2013.08.0172
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