Safe and effective medications for pain disorders
are limited. Males and females may experience pain
differently; however, little is known about the biology
of pain disorders. Evidence suggests that neurosteroids
(naturally occurring substances in the brain
and body) may play a role in the biology of pain.
Our preliminary findings show that DHEAS (neurosteroid)
is lower in women who report higher levels
of back pain. This could mean that women with
lower DHEAS levels are at greater risk of developing
pain than women with higher levels of DHEAS.
Therefore, increasing DHEAS levels may prevent or
improve pain in female Veterans.
Volume 53 Number 4, 2016
Pages 499 — 510
Go to TOP
Last Reviewed or Updated Wednesday, July 27, 2016 12:55 PM